"Orthopaedic infections represent common, potentially devastating, and sometimes fatal complications that can occur after any surgery. Infections associated with orthopaedic trauma are especially prevalent, and there is an increasing incidence of bone infections linked to a greater number of joint arthroplasties being performed annually. Management of Orthopaedic Infections: A Practical Guide by renowned orthopaedic surgeon and researcher Antonia Chen is a practical clinical reference to assist clinicians in the diagnosis and treatment of challenging infections spanning the entire orthopaedic specialty"--.

• Management of Orthopaedic Infections: A Practical Guide
• MedOne Access Information
• Title
• Copyright
• Dedication
• Contents
• 1 Detection of Microbes in Orthopaedic Infections
  • 1.1 Introduction
  • 1.2 Culture-Based Microbiology
    • 1.2.1 Limitations of Culture-Based Microbiology
    • 1.2.2 Detection of Microbes in Biofilm
    • 1.2.3 Infections with Atypical Organisms
    • 1.2.4 Orthopaedic Hardware Infections
    • 1.2.5 Native Bone and Joint Infections
  • 1.3 Molecular Techniques
    • 1.3.1 Polymerase Chain Reaction (PCR)
    • 1.3.2 Next-Generation Sequencing (NGS)
  • 1.4 Conclusions
• 2 Antibiotics for Orthopaedic Infections
  • 2.1 Systemic Antibiotics
    • 2.1.1 Definitions
    • 2.1.2 Antibiotic Selection and Administration
    • 2.1.3 Intravenous versus Oral Antibiotics
  • 2.2 Antiseptics
    • 2.2.1 Povidone-Iodine
    • 2.2.2 Chlorhexidine (Gluconate/Digluconate)
  • 2.3 Carriers that may be Associated with Antibiotics
    • 2.3.1 Nondegradable
    • 2.3.2 Biodegradable
  • 2.4 Antibiotics for Use in Carriers
    • 2.4.1 Gentamicin/Tobramycin
    • 2.4.2 Vancomycin
  • 2.5 Topical Antibiotics
  • 2.6 Treatment Failure
  • 2.7 Collaboration between Orthopaedic Surgeons and Infectious Disease Specialists
  • 2.8 Conclusion
• 3 Irrigation Solutions for Orthopaedic Infections
  • 3.1 Acetic Acid
    • 3.1.1 Overview of Antiseptic Agents
    • 3.1.2 Efficacy as Surgical Wound Irrigant
  • 3.2 Bacitracin and Polymyxin
    • 3.2.1 Overview of Antiseptic Agent
    • 3.2.2 Efficacy as a Surgical Wound Irrigant
  • 3.3 Dilute Povidone-Iodine (PI)
    • 3.3.1 Overview of Antiseptic Agent
    • 3.3.2 Efficacy as a Surgical Wound Irrigant
  • 3.4 Chlorhexidine
    • 3.4.1 Overview of Antiseptic Agent
    • 3.4.2 Efficacy as a Surgical Wound Irrigant
  • 3.5 Sodium Hypochlorite (NaOCl)
    • 3.5.1 Overview of Antiseptic Agent
    • 3.5.2 Efficacy as a Surgical Wound Irrigant
  • 3.6 Hydrogen Peroxide
    • 3.6.1 Overview of Antiseptic Agent
    • 3.6.2 Efficacy as a Surgical Wound Irrigant
  • 3.7 Conclusion
• 4 Surgical Wound Dressings after Treating Orthopaedic Infections
  • 4.1 Introduction
  • 4.2 Characteristics of Optimal Surgical Dressings
  • 4.3 Dressing Types
    • 4.3.1 Nonocclusive and Occlusive Dressings
    • 4.3.2 Dressing Application Tips and Tricks
    • 4.3.3 Wound Vacuum Systems
  • 4.4 Algorithm for Surgical Dressing Selection
  • 4.5 Conclusion
• 5 Osteomyelitis
  • 5.1 Introduction
  • 5.2 Terminology
  • 5.3 Classification
    • 5.3.1 Type 1 (Medullary)
    • 5.3.2 Type 2 (Superficial)
    • 5.3.3 Type 3 (Localized)
    • 5.3.4 Type 4 (Diffuse)
  • 5.4 Diagnosis
    • 5.4.1 Clinical Features
    • 5.4.2 Laboratory Tests
    • 5.4.3 Imaging
    • 5.4.4 Microbiological Diagnosis
    • 5.4.5 Histological Diagnosis
  • 5.5 Diagnostic Criteria
  • 5.6 Microbiology
  • 5.7 Treatment of Osteomyelitis
    • 5.7.1 General Considerations
    • 5.7.2 Acute Osteomyelitis
    • 5.7.3 Chronic Osteomyelitis
    • 5.7.4 Operative Treatment
    • 5.7.5 Tissue Sampling
    • 5.7.6 Tissue Excision
    • 5.7.7 Antimicrobial Therapy
    • 5.7.8 Dead Space Management
    • 5.7.9 Bone Stabilization
    • 5.7.10 Soft-Tissue Coverage
    • 5.7.11 Staging of Surgery
  • 5.8 Conclusion
• 6 Treatment of the Septic Native Joint
  • 6.1 Introduction
  • 6.2 Diagnosis
    • 6.2.1 Risk Factors
    • 6.2.2 Joint Involvement
    • 6.2.3 Clinical Manifestations
    • 6.2.4 Serum Evaluation
    • 6.2.5 Synovial Analysis
    • 6.2.6 Imaging
  • 6.3 Treatment
    • 6.3.1 Common Organisms
    • 6.3.2 Gonococcal Arthritis
    • 6.3.3 Other Pathogens
    • 6.3.4 Antimicrobial Therapy
    • 6.3.5 Surgical Treatment
    • 6.3.6 Needle Aspiration
    • 6.3.7 Arthroscopic Treatment
    • 6.3.8 Open Treatment
  • 6.4 Conclusion
• 7 Management of Periprosthetic Joint Infection
  • 7.1 Introduction
  • 7.2 Chronicity of Infection
  • 7.3 Antibiotic Management Alone
  • 7.4 Irrigation and Debridement
    • 7.4.1 Irrigation and Debridement without Polyethylene Exchange
  • 7.5 DAIR
  • 7.6 One-Stage Exchange Arthroplasty
    • 7.6.1 Preparation
    • 7.6.2 Debridement
    • 7.6.3 Temporary Closure
    • 7.6.4 New Prosthesis Implantation
    • 7.6.5 Outcomes of One-Stage Exchange Arthroplasty
  • 7.7 Two-Stage Exchange Arthroplasty
    • 7.7.1 First Stage: Debridement and Antibiotic Spacer Implantation
    • 7.7.2 Second Stage: Reimplantation
    • 7.7.3 Outcomes of Two-Stage Exchange Arthroplasty
  • 7.8 Salvage Procedures for PJI
  • 7.9 Conclusion
• 8 Infection after Fracture Fixation and Infected Nonunions
  • 8.1 Antibiotic Prophylaxis for Open Fractures
  • 8.2 Diagnosis
    • 8.2.1 Clinical Diagnosis
    • 8.2.2 Laboratory Tests
  • 8.3 Imaging
    • 8.3.1 Radiography
    • 8.3.2 Computed Tomography
    • 8.3.3 Magnetic Resonance Imaging
    • 8.3.4 Nuclear Medicine Studies
  • 8.4 Microbiology
    • 8.4.1 Cultures
    • 8.4.2 Common Organisms
  • 8.5 Surgical Treatment
    • 8.5.1 Irrigation Solutions
    • 8.5.2 Pin Tract Infections
    • 8.5.3 Irrigation and Debridement with Hardware Retention
    • 8.5.4 Irrigation and Debridement with Hardware Removal
    • 8.5.5 Irrigation and Debridement and Revision Fracture Surgery—One-Stage
    • 8.5.6 Irrigation and Debridement with Hardware Removal and Antibiotic Spacer Placement—Two-Stage
  • 8.6 Soft-Tissue Coverage
  • 8.7 Antibiotics
  • 8.8 Conclusion
• 9 Spine Infections
  • 9.1 Spinal Epidural Abscesses
    • 9.1.1 Introduction and Epidemiology
    • 9.1.2 Anatomy and Pathogenesis
    • 9.1.3 Presentation and Diagnosis
    • 9.1.4 Management and Surgical Decision-Making
    • 9.1.5 Prognosis
  • 9.2 Vertebral Osteomyelitis and Diskitis
    • 9.2.1 Introduction and Epidemiology
    • 9.2.2 Anatomy and Pathogenesis
    • 9.2.3 Presentation and Diagnosis
    • 9.2.4 Management and Surgical Decision-Making
    • 9.2.5 Prognosis
  • 9.3 Conclusion
• 10 Graft Infections
  • 10.1 Introduction
  • 10.2 Risk Factors for Graft Infection
    • 10.2.1 The Effect of Graft Type on Rates of Postoperative Infection
  • 10.3 Clinical Presentation and Management
    • 10.3.1 Clinical Presentation
    • 10.3.2 Laboratory Evaluation
    • 10.3.3 Surgical Site Infection versus Intra-articular Graft Infection
    • 10.3.4 Organisms Responsible for Graft Infection
  • 10.4 Management of Graft Infection
    • 10.4.1 Nonsurgical Management
    • 10.4.2 Surgical Management of Graft Infection
    • 10.4.3 Graft Retention
    • 10.4.4 Hardware Retention
    • 10.4.5 Graft Replantation
    • 10.4.6 Antibiotic Management
  • 10.5 Outcomes and Complications
    • 10.5.1 Recurrent Instability and Reoperation
    • 10.5.2 Patient Reported Outcomes Following Graft Infection
    • 10.5.3 Graft Infection Cost
  • 10.6 Graft Infection Prevention
    • 10.6.1 Intraoperative Graft Antibiotics
  • 10.7 Intraoperative Autograft Contamination
  • 10.8 Conclusion
• Index
• Additional MedOne Access Information