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Arthroplasty in hand surgery: FESSH instructional course book 2020 / [edited by] Stephan F. Schindele, Grey Giddins, Philippe Bellemère. — 1 online resource — <URL:http://elib.fa.ru/ebsco/2974375.pdf>.

Дата создания записи: 06.01.2022

Тематика: Hand — Surgery.; Arthroplasty.; Hand Joints — surgery.; Arthroplasty — methods.; Arthroplasty; Hand — Surgery

Коллекции: EBSCO

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"Recent research suggests the lifetime risk of hand arthritis may be greater than 40%. Concurrently, advances in small joint arthroplasty have greatly improved the treatment and outcomes in patients following trauma or suffering from arthritis, joint stiffness, and instability of joints in the hand and wrist. Arthroplasty in Hand Surgery: FESSH Instructional Course Book 2020 provides in-depth coverage of the surgical reconstruction or replacement of these joints. Edited by renowned hand surgeons Stephan Schindele, Grey Giddins, and Philippe Bellemère, this unique resource features contributions from an international who's who of experts. Organized in five sections and 35 chapters, the generously illustrated book encompasses the full spectrum of modern arthroplasty techniques. In section one, the anatomy, biomechanics, and mode of action of the finger and thumb joints are discussed. It concludes with an intriguing history of hand arthroplasty. Sections two to four cover the latest arthroplasty procedures to treat impaired joints of the fingers (including proximal interphalangeal and distal interphalangeal), thumb, and wrist, respectively. The last section discusses arthroplasty of the distal radioulnar joint. This highly practical resource is essential reading for surgeons in training and practicing orthopaedic surgeons and hand specialists"--.

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  • Arthroplasty in Hand Surgery: FESSH Instructional Course Book 2020
  • Title
  • Copyright
  • Contents
  • Preface
  • Contributors
  • Section 1 General
    • 1 The Anatomy and Functional Importance of Finger Joints: A Short Atlas
      • 1.1 Introduction
    • 2 Biomaterials in Arthroplasty of the Hand
      • 2.1 Introduction
      • 2.2 Behavior of Biomaterials
        • 2.2.1 Biocompatibility
        • 2.2.2 Nontoxicity
        • 2.2.3 Corrosion Resistance
        • 2.2.4 Strength
        • 2.2.5 Modulus of Elasticity
        • 2.2.6 Fatigue Resistance
        • 2.2.7 Wear Resistance
        • 2.2.8 Creep Resistance
        • 2.2.9 Osteointegration
      • 2.3 Classical Biomaterials
        • 2.3.1 Polymers
        • 2.3.2 “Nouvelle Vague” for Hand Arthroplasty Development
        • 2.3.3 Surface Treatment to Improve Bone Bonding
        • 2.3.4 Pyrolytic Carbon
      • 2.4 The Limitations of Current Materials
      • 2.5 Future of Biomaterials in Hand Arthroplasty
      • 2.6 Conclusion
    • 3 Proprioception and Neural Feedback in Thumb and Wrist Arthroplasty
      • 3.1 Basis of Proprioception for Joint Control
        • 3.1.1 Conscious Proprioception Senses
        • 3.1.2 Unconscious Proprioception Senses
        • 3.1.3 Sensory Nerve Endings
      • 3.2 Innervation Patterns
        • 3.2.1 Wrist
        • 3.2.2 Trapeziometacarpal Joint
        • 3.2.3 Distal Radioulnar Joint (DRUJ)
      • 3.3 Innervation Patterns in Osteoarthritis
      • 3.4 Neural Feedback of the Wristand Thumb
      • 3.5 Clinical Implications
        • 3.5.1 The Case for Nerve-Sparing Surgery
        • 3.5.2 The Case for Denervation
      • 3.6 In Conclusion—to Denervate or Reinnervate?
    • 4 Outcome Measurement in Hand and Wrist Arthroplasty
      • 4.1 Introduction
      • 4.2 Frequently Used PROMs Suitable for Patients Undergoing Hand Arthroplasty
        • 4.2.1 Michigan Hand Outcomes Questionnaire (MHQ)8/Brief MHQ
        • 4.2.2 Patient-Rated Wrist Evaluation(PRWE)
        • 4.2.3 Disability of the Arm, Shoulder, and Hand Questionnaire (DASH)21/QuickDASH
        • 4.2.4 Patient-Reported OutcomesMeasurement Information System (PROMIS)
        • 4.2.5 Patient-Specific Functional Scale (PSFS)
        • 4.2.6 Single Assessment Numeric Evaluation (SANE) Score
        • 4.2.7 Quality-of-Life Measures
        • 4.2.8 Further Validated Hand-Specific PROMs
      • 4.3 Core Sets
      • 4.4 Measurement Properties
        • 4.4.1 Reliability
        • 4.4.2 Validity
        • 4.4.3 Responsiveness
        • 4.4.4 Interpretability
      • 4.5 Choosing an Appropriate Outcome Measure
      • 4.6 Collecting and Processing Outcome Measures
      • 4.7 Interpretation of Outcomes
        • 4.7.1 Minimal Important Difference (MID) and Minimal Important Change (MIC)
        • 4.7.2 Patient Acceptable Symptom State (PASS)
      • 4.8 Conclusion
    • 5 The Norwegian Arthroplasty Register
      • 5.1 Introduction
      • 5.2 Wrist Replacements
        • 5.2.1 Method
        • 5.2.2 Results
      • 5.3 CMC IA Replacements
        • 5.3.1 Results
      • 5.4 Finger Joint Replacement
        • 5.4.1 MCP Joint Replacement
        • 5.4.2 PIP Joint Replacement
    • 6 The History of Arthroplasty in the Hand and Wrist
      • 6.1 The Very Early History
        • 6.1.1 The Era of Zeus and His Fellow Gods
        • 6.1.2 Amputation—Upper Paleolithic to the Middle Ages
      • 6.2 Milestones in the Modern History of Wrist Arthroplasty
        • 6.2.1 Resection Arthroplasty
        • 6.2.2 Interposition Arthroplasty
        • 6.2.3 The First Total Knee and Wrist Replacement—Themistocles Gluck (1853–1942)
        • 6.2.4 The Concept of Flexible Implant Arthroplasty—Alfred B. Swanson (1923–2016)
      • 6.3 Early Design Developments in Wrist Arthroplasty
        • 6.3.1 First Generation: Elastomer Flexible Hinge Design
        • 6.3.2 Second Generation: Multicomponent Implants
      • 6.4 Contemporary Designs in Wrist Arthroplasty
        • 6.4.1 Third Generation: Minimal Bone Resection
      • 6.5 Arthroplasty of the Distal Radioulnar Joint (DRUJ)
        • 6.5.1 Resection/Interposition Arthroplasty
        • 6.5.2 Ulna Head Replacement
        • 6.5.3 Partial Ulna Head Replacement
        • 6.5.4 Total DRUJ Replacement
      • 6.6 Arthroplasty of Metacarpophalangeal and Proximal Interphalangeal Joints
        • 6.6.1 Resection/Interposition Arthroplasty
        • 6.6.2 Transplant Arthroplasty
        • 6.6.3 Hinged Implant Arthroplasty
        • 6.6.4 One-Piece Polymer Arthroplasty
        • 6.6.5 Metalloplastic Arthroplasty
        • 6.6.6 Surface Replacement Arthroplasty
        • 6.6.7 Pyrocarbon Implant Arthroplasty
      • 6.7 Arthroplasty of the Trapeziometacarpal (TMC) Joint
        • 6.7.1 Interposition Arthroplasty
        • 6.7.2 Hemiarthroplasty of the TMC Joint
        • 6.7.3 Total TMC Arthroplasty
  • Section 2 Arthroplasty of Finger Joints
    • Section 2A MCP Arthroplasty
      • 7 Failure Analysis of Silicone Implants in Metacarpophalangeal and Proximal Interphalangeal Joints
        • 7.1 Introduction
        • 7.2 Failure Mechanisms
        • 7.3 Material Properties
        • 7.4 Improving Silicone Implants
        • 7.5 Conclusion
      • 8 Silicone Interposition Arthroplasty for MCP and PIP joints
        • 8.1 Introduction
        • 8.2 Characteristics of Silicone Implants
        • 8.3 MCP Joint Arthroplasty
          • 8.3.1 Indications
          • 8.3.2 Contraindications
          • 8.3.3 Preoperative Evaluation
          • 8.3.4 Surgical Anatomy
          • 8.3.5 Approach
          • 8.3.6 Authors’ Preferred Technique
          • 8.3.7 Postoperative Care
          • 8.3.8 Expected Outcomes
        • 8.4 PIP Joint Arthroplasty
          • 8.4.1 Indications
          • 8.4.2 Contraindications
          • 8.4.3 Preoperative Evaluation
          • 8.4.4 Surgical Anatomy
          • 8.4.5 Approach
          • 8.4.6 Authors’ Preferred Technique
          • 8.4.7 Postoperative Care
          • 8.4.8 Expected Outcomes
      • 9 Surface Gliding Implants for the Metacarpophalangeal Joints
        • 9.1 Introduction
        • 9.2 Characteristics of Surface Gliding Implants
          • 9.2.1 Pyrocarbon
          • 9.2.2 Surface Replacement Arthroplasty (SRA) MCP joint
        • 9.3 Indications/Contraindications
        • 9.4 Results in the Literature
          • 9.4.1 Pyrocarbon
          • 9.4.2 Surface Replacement Arthroplasty (SRA)
        • 9.5 Personal Experience (Pearls/Pitfalls)
        • 9.6 Conclusion
      • 10 Vascularized Toe Joint Transfers for Proximal Interphalangeal and Metacarpophalangeal Joint Reconstruction
        • 10.1 Introduction
        • 10.2 Anatomical Bases for Joint Transfer to the Hand
          • 10.2.1 Arterial Network
          • 10.2.2 Venous Drainage of Toe Joint Transfers
        • 10.3 Indications for Toe Joint Transfers
        • 10.4 Surgical Technique for PIP Transfer from the Second Toe
          • 10.4.1 Preparation of the Recipient Site
          • 10.4.2 Dissection of Transplant (Donor Site)
          • 10.4.3 In Situ Arrangement of Transplant
          • 10.4.4 Reconstruction of Donor Site
        • 10.5 Surgical Technique for MTP Transfer from the Second Toe
        • 10.6 Outcomes of Vascularized Toe Joint Transfers
          • 10.6.1 PIP Joint Reconstruction
          • 10.6.2 MCP Reconstruction
        • 10.7 Discussion
        • 10.8 Conclusion
    • Section 2B PIP and DIP Arthroplasty
      • 11 The Treatment Strategy in PIP Arthroplasty
        • 11.1 Introduction
          • 11.1.1 Anatomical Considerations for PIP Arthroplasty
          • 11.1.2 Evaluation of PIP Joint Problems
          • 11.1.3 Nonoperative Treatment of PIP Destruction
        • 11.2 PIP Joint Replacement
          • 11.2.1 General Remarks
          • 11.2.2 Choice of Implants
          • 11.2.3 Combination of Different Interventions
        • 11.3 Strategies and Indications in the Treatment of PIP Joint Destruction
          • 11.3.1 Case Example
          • 11.3.2 Revision of Failed PIP Arthroplasty
          • 11.3.3 Discussion of the Case Example
      • 12 Second-Generation Surface Gliding Proximal Interphalangeal Joint Implants (Metal, Pyrocarbon, and Ceramic)
        • 12.1 Introduction
        • 12.2 Characteristic of Implant or Technique
          • 12.2.1 SR-PIP Prosthesis
          • 12.2.2 Pyrocarbon Prosthesis
          • 12.2.3 Ceramic Prosthesis
        • 12.3 Indication and Contraindication
        • 12.4 Results in the Literature
          • 12.4.1 Results for SR-PIP
          • 12.4.2 Results for Pyrocarbon PIP Arthroplasties
          • 12.4.3 Results for the Ceramic PIP Arthroplasty
        • 12.5 Authors’ Own Experience and Preferred Technique: Tips and Tricks
      • 13 Third-Generation PIP Joint Arthroplasty: Tactys
        • 13.1 Introduction
        • 13.2 Development
        • 13.3 Characteristics of the Implant
          • 13.3.1 Surgical Technique
          • 13.3.2 Indications/Contraindications
          • 13.4 Results in the Literature
          • 13.5 Author’s Own Experience
          • 13.6 Tips and Tricks
      • 14 Third-Generation PIP Arthroplasty: CapFlex-PIP
        • 14.1 Introduction
        • 14.2 Characteristic of Implant
        • 14.3 Indication and Contraindication
        • 14.4 Results in the Literature
        • 14.5 Author’s Own Experience and Preferred Technique
          • 14.5.1 Author’s Preferred Technique
          • 14.5.2 After-Care
          • 14.5.3 Author’s Own Results
      • 15 Third-Generation PIP Arthroplasty: The PIP-R
        • 15.1 Design Rationale
        • 15.2 Design Features
        • 15.3 Indications
        • 15.4 Contraindications
        • 15.5 Published Results
        • 15.6 Author’s Results
        • 15.7 How We Do the Procedure and Tips
        • 15.8 Rehabilitation
      • 16 Surgical Approaches for PIP Joint Arthroplasty
        • 16.1 Introduction
        • 16.2 Dorsal Approach
          • 16.2.1 Dorsal Skin Incision
          • 16.2.2 Dorsal Tenotomy to the PIP Joint
        • 16.3 Lateral Approach
        • 16.4 Volar Approach
        • 16.5 Literature Review and Authors’ Preferred Technique
      • 17 Joint Replacement of Osteoarthritic and Posttraumatic Distal Interphalangeal Joints
        • 17.1 Introduction
        • 17.2 Characteristic of Silicone Implants for DIP Joint
        • 17.3 Own Results in the Literature
        • 17.4 Own Experience and Preferred Technique for DIP Joint Arthroplasty
        • 17.5 Postoperative Care
        • 17.6 Technique Modification
        • 17.7 Thumb-IP-Joint Arthroplasty with Silicone Implant
        • 17.8 Skin Closure
        • 17.9 Discussion
  • Section 3 Arthroplasty of the Thumb
    • 18 Silicone Implants and Total Joint Prostheses for Osteoarthritis of the Trapeziometacarpal Joint: A Systematic Review
      • 18.1 Introduction
      • 18.2 Materials and Methods
      • 18.3 Results
        • 18.3.1 Silicone Implants
        • 18.3.2 Total Trapeziometacarpal Joint Implants
      • 18.4 Discussion
    • 19 Pi2 and Nugrip Pyrocarbon Arthroplasties of the Thumb CMC Joint
      • 19.1 Introduction
      • 19.2 Characteristic of Implants
        • 19.2.1 Pi2
        • 19.2.2 Nugrip
      • 19.3 Results in the Literature
        • 19.3.1 Pi2
        • 19.3.2 Nugrip
      • 19.4 Indications/Contraindications
        • 19.4.1 Indications
        • 19.4.2 Contraindications
      • 19.5 Pi2 Implant: Author’s Own Experience and Preferred Technique
        • 19.5.1 Anteroexternal Approach
        • 19.5.2 Nontraumatic Trapeziectomy
        • 19.5.3 Partial Trapezoidectomy
        • 19.5.4 Placing a Trial Implant and the Final Implant
        • 19.5.5 Capsuloplasty and Ligament Reconstruction
        • 19.5.6 Closure and X-Rays
        • 19.5.7 Postoperative Care and Rehabilitation
        • 19.5.8 Possible Complementary Procedures
    • 20 Pyrocardan and Pyrodisk Arthroplasties of the Thumb CMC Joint
      • 20.1 Introduction
      • 20.2 Pyrodisk
        • 20.2.1 Characteristics of the Implant
        • 20.2.2 Indications
        • 20.2.3 Surgical Technique
        • 20.2.4 Results in the Literature
        • 20.2.5 Author’s Experience
      • 20.3 Pyrocardan
        • 20.3.1 Characteristics of the Implant
        • 20.3.2 Indications
        • 20.3.3 Surgical Technique
        • 20.3.4 Results in the Literature
        • 20.3.5 Author’s Experience
      • 20.4 Tips and Tricks for Pyrodisk and Pyrocardan Implants
      • 20.5 Conclusion
    • 21 Total Thumb CMC Arthroplasty
      • 21.1 Introduction
      • 21.2 Historical Aspects
      • 21.3 Different Types of Total CMC Arthroplasty (TCA)
        • 21.3.1 The Models
      • 21.4 Surgical Technique
        • 21.4.1 Surgical Approaches for TCA
        • 21.4.2 Steps for Insertion
        • 21.4.3 Postoperative Care
      • 21.5 Results
        • 21.5.1 Results of the Prosthesis
        • 21.5.2 Comparison with Trapeziectomies
        • 21.5.3 Complications
        • 21.5.4 Revision
      • 21.6 Indications
      • 21.7 Conclusion
    • 22 STT and Peritrapezium Joints Arthroplasties
      • 22.1 Introduction
      • 22.2 Pyrocarbon Implants for STT Arthroplasty
        • 22.2.1 Indications
        • 22.2.2 STPI
        • 22.2.3 Pyrocardan Implant in STT Joint
      • 22.3 Double Pyrocarbon Interposition for Peritrapezial OA: “Burger Arthroplasty”
        • 22.3.1 Indications
        • 22.3.2 Surgical Technique
        • 22.3.3 Author’s Experience
      • 22.4 Conclusion
    • 23 Thumb IP Joint Arthroplasty: An Alternative to Arthrodesis
      • 23.1 Introduction
        • 23.1.1 Treatment Strategies at the Thumb IP Joint
        • 23.1.2 Arthroplasty
      • 23.2 Characteristics of Possible Implants for Thumb IP Joint Replacement
      • 23.3 Indications and Contraindications for Thumb IP Joint Replacement
      • 23.4 Published Outcomes and Our Own Results
      • 23.5 Author’s Own Experience and Preferred Technique (Tips and Tricks)
  • Section 4 Arthroplasty of the Wrist
    • 24 Systematic Review of Wrist Arthroplasty
      • 24.1 Introduction
        • 24.1.1 Evolution of Total Wrist Arthroplasty
        • 24.1.2 Current Implants
      • 24.2 Objectives
      • 24.3 Methods
        • 24.3.1 Study Inclusion Criteria
        • 24.3.2 Search Methods
        • 24.3.3 Data Collection and Analysis
      • 24.4 Results
        • 24.4.1 Description of Studies
        • 24.4.2 Effects of Interventions
      • 24.5 Discussion
    • 25 Surface Replacement Wrist Arthroplasty
      • 25.1 Introduction
      • 25.2 Implants
      • 25.3 Indications and Contraindications
      • 25.4 Results in the Literature (Short Version)
        • 25.4.1 Complications
        • 25.4.2 Functional Results
        • 25.4.3 Implant Durability
      • 25.5 Authors’ Own Experience and Preferred Technique (Tips and Tricks)
        • 25.5.1 Personal Experience
        • 25.5.2 Revision Surgery
        • 25.5.3 Tips and Tricks
    • 26 Ball-and-Socket Wrist Arthroplasty
      • 26.1 History of Ball-and-Socket Wrist Arthroplasty
        • 26.1.1 Meuli Wrist Arthroplasty
      • 26.2 Development of a New Ball-and-Socket Arthroplasty
        • 26.2.1 Fixation
        • 26.2.2 Articulation
      • 26.3 Introduction of a New Arthroplasty
        • 26.3.1 The Implant
        • 26.3.2 Patient Selection
        • 26.3.3 Surgical Method and Follow-Up
        • 26.3.4 Results
        • 26.3.5 Revisions
      • 26.4 Conclusion
    • 27 Wrist Hemiarthroplasty for Acute Irreparable Distal Radius Fracture in the Independent Elderly
      • 27.1 Introduction
      • 27.2 Current Therapeutic Options for Acute IDRF in the Independent Elderly
      • 27.3 Current Evidence
      • 27.4 Authors’ Experience
      • 27.5 Conclusion
    • 28 Pyrocarbon Implants in the Wrist: Amandys and RCPI
      • 28.1 Introduction
      • 28.2 Amandys Implant
        • 28.2.1 Characteristics of the Implant
        • 28.2.2 Indications and Contraindications
        • 28.2.3 Surgical Technique
        • 28.2.4 Associated Procedures
        • 28.2.5 Results
        • 28.2.6 Pitfalls, Tips, and Tricks
        • 28.2.7 Summary
      • 28.3 RCPI Implant
        • 28.3.1 Characteristics of Implant
        • 28.3.2 Indications and Contraindications
        • 28.3.3 Surgical Technique
        • 28.3.4 Results in the Literature
        • 28.3.5 Author’s Own (AM) Experience and Preferred Technique
      • 28.4 Conclusion
    • 29 Partial Wrist Joint Arthroplasties: APSI, Capitolunate Joint, Pisotriquetral Joint, and Little Finger Carpometacarpal Joint
      • 29.1 APSI: Adaptative Proximal Scaphoid Implant
        • 29.1.1 Introduction
        • 29.1.2 Implant and Surgical Technique
        • 29.1.3 Indication and Contraindication
        • 29.1.4 Results in Literature
        • 29.1.5 Comparison with Other Techniques
      • 29.2 Capitolunate Joint Arthroplasty
        • 29.2.1 Introduction
        • 29.2.2 Pi2 and RCPI Implants
        • 29.2.3 Surgical Technique and Indication
        • 29.2.4 Results in Literature and in Our Experience
      • 29.3 Pisotriquetral Joint Arthroplasty
        • 29.3.1 Introduction
        • 29.3.2 Implant Pyrocardan
        • 29.3.3 Surgical Technique and Management
        • 29.3.4 Results in Our Experience
      • 29.4 Little Finger Carpometacarpal Joint Arthroplasty
        • 29.4.1 Introduction
        • 29.4.2 Current Surgical Techniques
        • 29.4.3 Our Approach and Management
      • 29.5 Conclusion
    • 30 Revision Wrist Arthroplasty
      • 30.1 Introduction
      • 30.2 Causes of Failure of a Wrist Arthroplasty
        • 30.2.1 Infection
        • 30.2.2 Aseptic Loosening
        • 30.2.3 Implant Fracture
        • 30.2.4 Biomechanical Mismatch
      • 30.3 Managing Bone Loss
        • 30.3.1 Bone Grafting
        • 30.3.2 Wrist Arthrodesis
        • 30.3.3 Resection Arthroplasty
        • 30.3.4 Summary of Options for Revision of a Wrist Arthroplasty
      • 30.4 Revision Arthroplasty Technique
        • 30.4.1 Technique
        • 30.4.2 The Technique Steps
      • 30.5 Unit Experience at Wrightington Hospital
        • 30.5.1 Unit Experience Background
        • 30.5.2 Survivorship of the Revision TWA in Our Series
        • 30.5.3 Comparison with Other Units
      • 30.6 Summary
  • Section 5 Arthroplasty of the DRUJ
    • 31 Systematic Review of Distal Radioulnar Joint (DRUJ) Arthroplasty
      • 31.1 Introduction
      • 31.2 Methods
        • 31.2.1 Inclusion Criteria
        • 31.2.2 Exclusion Criteria
        • 31.2.3 Literature Search
        • 31.2.4 Outcome Measures
        • 31.2.5 Assessment of the Level of Evidence
        • 31.2.6 Assessment of Methodological Quality
        • 31.2.7 Assessment of Survivorship
      • 31.3 Results
        • 31.3.1 Studies Identified
        • 31.3.2 Implant Types
        • 31.3.3 Literature Quality and Risk of Bias
      • 31.4 Discussion
      • 31.5 Conclusions
    • 32 First Choice Distal Radioulnar Joint Arthroplasty
      • 32.1 Introduction
      • 32.2 Implant Characteristics
      • 32.3 Surgical Technique
      • 32.4 Indications
      • 32.5 Results in the Literature
      • 32.6 Author’s Own Experience
    • 33 UHP DRUJ Arthroplasty
      • 33.1 Introduction
      • 33.2 Herbert Ulnar Head Prosthesis
      • 33.3 Operative Technique
      • 33.4 Indications
      • 33.5 Contraindications
      • 33.6 Results
        • 33.6.1 Results in the Literature
        • 33.6.2 Patient Example
      • 33.7 Conclusion
    • 34 Eclypse Distal Radioulnar Joint Arthroplasty
      • 34.1 Introduction
      • 34.2 Characteristics of the Implant and Technique
        • 34.2.1 Technique
      • 34.3 Indications and Contraindications
      • 34.4 Results in the Literature
      • 34.5 Author’s Experience and Preferred Technique (Tips and Tricks)
        • 34.5.1 Results
        • 34.5.2 Tips and Tricks
    • 35 Salvage Distal Radioulnar Joint Arthroplasty with the Aptis Implant
      • 35.1 Introduction
      • 35.2 The Implant and Technique
      • 35.3 Indications and Contraindications
      • 35.4 Results in the Literature
      • 35.5 Authors’ Own Experience and Preferred Technique (Tips and Tricks)
      • 35.6 Conclusions
  • Index

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