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Kaltashov, Igor A.,. Mass Spectrometry in Biopharmaceutical Analysis / Igor A. Kaltashov, Shunhai Wang, Guanbo Wang. — 1 online resource (X, 270 p.). — In English. — <URL:http://elib.fa.ru/ebsco/3102551.pdf>.

Record create date: 11/29/2021

Subject: Biopharmaceutics.; Biopharmaceutics; Biochemische Analyse.; Massenspektrometrie.; Spektroskopie.; Strukturanalyse.; Biopharmacie.; SCIENCE / Chemistry / General.; Biopharmaceutics.; Biochemical Analysis.; Mass Spectroscopy.; Spectroscopy.; Structural Analysis.

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Biopharmaceuticals are a unique class of compounds due to their extreme structural complexity. The current text puts together a variety of the state-of-the art approaches that use mass spectrometry to evaluate various aspects of biopharmaceutical products ranging from monitoring stress-related structural changes to their quantitation in pharmacokinetic studies.

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Preface
Contents
Chapter 1 Analytical chemistry in biopharma
Chapter 2 A brief overview of biological mass spectrometry: concepts and definitions
Chapter 3 Characterization of covalent structure of protein therapeutics
Chapter 4 Characterization of higher order structure and protein interactions
Chapter 5 Biosimilars and comparability studies
Chapter 6 Characterization of impurities in biopharmaceutical products
Chapter 7 Quantitation of protein therapeutics in biological samples
Chapter 8 Non-protein biopharmaceuticals and related macromolecular drugs
Chapter 9 What is next?
Index

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